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1

Mucosal delivery of tuberculosis vaccines: a review of current approaches and challenges

Stylianou, Elena, Paul, Matthew J., Reljic, Rajko, McShane, Helen

Journal:

Expert Review of Vaccines

Year:

2019

Language:

english

File:

PDF, 1.85 MB

english, 2019

2

Dementia and Physical Activity (DAPA) - an exercise intervention to improve cognition in people with mild to moderate dementia: study protocol for a randomized controlled trial

Atherton, Nicky, Bridle, Chris, Brown, Deborah, Collins, Helen, Dosanjh, Sukhdeep, Griffiths, Frances, Hennings, Susie, Khan, Kamran, Lall, Ranjit, Lyle, Samantha, McShane, Rupert, Mistry, Dipesh, Nic

Journal:

Year:

2016

Language:

english

File:

PDF, 676 KB

english, 2016

3

Human Immunodeficiency Virus Infection Impairs Th1 and Th17 Mycobacterium tuberculosis–Specific T-Cell Responses

Murray, Lyle W, Satti, Iman, Meyerowitz, Jodi, Jones, Matthew, Willberg, Christian B, Ussher, James E, Goedhals, Dominique, Hurst, Jacob, Phillips, Rodney E, McShane, Helen, Vuuren, Cloete van, Frater

Journal:

The Journal of Infectious Diseases

Year:

2018

Language:

english

File:

PDF, 1.21 MB

english, 2018

4

Current approaches towards identifying a correlate of immune protection from tuberculosis

Satti, Iman, McShane, Helen

Journal:

Expert Review of Vaccines

Year:

2018

Language:

english

File:

PDF, 1.03 MB

english, 2018

5

Insights and challenges in tuberculosis vaccine development

Journal:

The Lancet Respiratory Medicine

Year:

2019

Language:

english

File:

PDF, 241 KB

english, 2019

6

High frequencies of circulating IFN-γ-secreting CD8 cytotoxic T cells specific for a novel MHC class I-restricted Mycobacterium tuberculosis epitope in M. tuberculosis-infected subjects without disease

Ansar A. Pathan, Katalin A. Wilkinson, Robert J. Wilkinson, Mohammed Latif, Helen McShane, Geoffrey Pasvol, Adrian V. S. Hill, Ajit Lalvani

Journal:

European Journal of Immunology

Year:

2000

Language:

english

File:

PDF, 135 KB

english, 2000

7

Biospecimen reporting for improved study quality (BRISQ)

Helen M. Moore, Andrea B. Kelly, Scott D. Jewell, Lisa M. McShane, Douglas P. Clark, Renata Greenspan, Daniel F. Hayes, Pierre Hainaut, Paula Kim, Elizabeth A. Mansfield, Olga Potapova, Peter Riegman,

Journal:

Cancer Cytopathology

Year:

2011

Language:

english

File:

PDF, 188 KB

english, 2011

8

CD8+ T cell-mediated suppression of intracellular Mycobacterium tuberculosis growth in activated human macrophages

Roger H. Brookes, Ansar A. Pathan, Helen McShane, Meike Hensmann, David A. Price, Adrian V. S. Hill

Journal:

European Journal of Immunology

Year:

2003

Language:

english

File:

PDF, 241 KB

english, 2003

9

Prime-boost immunisation strategies for tuberculosis

Helen McShane, Adrian Hill

Journal:

Microbes and Infection

Year:

2005

Language:

english

File:

PDF, 148 KB

english, 2005

10

Mycobacterium tuberculosisPPD-induced immune biomarkers measurablein vitrofollowing BCG vaccination of UK adolescents by multiplex bead array and intracellular cytokine staining

Steven G Smith, Maeve K Lalor, Patricia Gorak-Stolinska, Rose Blitz, Natalie ER Beveridge, Andrew Worth, Helen McShane, Hazel M Dockrell

Journal:

Year:

2010

Language:

english

File:

PDF, 912 KB

english, 2010

11

A New Vaccine for Tuberculosis: The Challenges of Development and Deployment

Helen A. Fletcher, Tony Hawkridge, Helen McShane

Journal:

Journal of Bioethical Inquiry

Year:

2009

Language:

english

File:

PDF, 180 KB

english, 2009

12

Recombinant modified vaccinia virus Ankara expressing antigen 85A boosts BCG-primed and naturally acquired antimycobacterial immunity in humans

McShane, Helen, Pathan, Ansar A, Sander, Clare R, Keating, Sheila M, Gilbert, Sarah C, Huygen, Kris, Fletcher, Helen A, Hill, Adrian V S

Journal:

Nature Medicine

Year:

2004

Language:

english

File:

PDF, 117 KB

english, 2004

13

Boosting BCG with MVA85A: the first candidate subunit vaccine for tuberculosis in clinical trials

Helen McShane, Ansar A. Pathan, Clare R. Sander, Nilu P. Goonetilleke, Helen A. Fletcher, Adrian V.S. Hill

Journal:

Year:

2005

Language:

english

File:

PDF, 183 KB

english, 2005

14

BCG: Myths, realities, and the need for alternative vaccine strategies

Helen McShane, William R. Jacobs, Paul E. Fine, Steven G. Reed, David N. McMurray, Marcel Behr, Ann Williams, Ian M. Orme

Journal:

Year:

2012

Language:

english

File:

PDF, 128 KB

english, 2012

15

Biospecimen reporting for improved study quality (BRISQ)

Helen M. Moore, Andrea Kelly, Lisa M. McShane, Jim Vaught

Journal:

Clinica Chimica Acta

Year:

2012

Language:

english

File:

PDF, 98 KB

english, 2012

16

Tuberculosis vaccines: progress and challenges

Anna M. Checkley, Helen McShane

Journal:

Trends in Pharmacological Sciences

Year:

2011

Language:

english

File:

PDF, 233 KB

english, 2011

17

Phase I clinical trial safety of DNA- and modified virus Ankara-vectored human immunodeficiency virus type 1 (HIV-1) vaccines administered alone and in a prime-boost regime to healthy HIV-1-uninfected volunteers

Inese Cebere, Lucy Dorrell, Helen McShane, Alison Simmons, Sheena McCormack, Claudia Schmidt, Carol Smith, Mary Brooks, Joanna E. Roberts, Simon C. Darwin, Patricia E. Fast, Christopher Conlon, Sarah

Journal:

Year:

2006

Language:

english

File:

PDF, 289 KB

english, 2006

18

Synergistic DNA–MVA prime-boost vaccination regimes for malaria and tuberculosis

Sarah C. Gilbert, Vasee S. Moorthy, Laura Andrews, Ansar A. Pathan, Samuel J. McConkey, Jenni M. Vuola, Sheila M. Keating, Tamara Berthoud, Daniel Webster, Helen McShane, Adrian V.S. Hill

Journal:

Year:

2006

Language:

english

File:

PDF, 208 KB

english, 2006

19

The effect of tuberculin skin test and BCG vaccination on the expansion of PPD-specific IFN-γ producing cells ex vivo

Martin O.C. Ota, Roger H. Brookes, Philip C. Hill, Patrick K. Owiafe, Hannah B. Ibanga, Simon Donkor, Timothy Awine, Helen McShane, Richard A. Adegbola

Journal:

Year:

2007

Language:

english

File:

PDF, 470 KB

english, 2007

20

Boosting BCG vaccination with MVA85A down-regulates the immunoregulatory cytokine TGF-β1

Helen A. Fletcher, Ansar A. Pathan, Tamara K. Berthoud, Susanna J. Dunachie, Kathryn T. Whelan, Nicola C. Alder, Clare R. Sander, Adrian V.S. Hill, Helen McShane

Journal:

Year:

2008

Language:

english

File:

PDF, 435 KB

english, 2008

21

Effect of vaccine dose on the safety and immunogenicity of a candidate TB vaccine, MVA85A, in BCG vaccinated UK adults

Ansar A. Pathan, Angela M. Minassian, Clare R. Sander, Rosalind Rowland, David W. Porter, Ian D. Poulton, Adrian V.S. Hill, Helen A. Fletcher, Helen McShane

Journal:

Year:

2012

Language:

english

File:

PDF, 864 KB

english, 2012

22

Early clinical trials with a new tuberculosis vaccine, MVA85A, in tuberculosis-endemic countries: issues in study design

Hannah B Ibanga, Roger H Brookes, Philip C Hill, Patrick K Owiafe, Helen A Fletcher, Christian Lienhardt, Adrian VS Hill, Richard A Adegbola, Helen McShane

Journal:

The Lancet Infectious Diseases

Year:

2006

Language:

english

File:

PDF, 1.00 MB

english, 2006

23

Vaccination against tuberculosis: How can we better BCG?

Pitt, Jonathan M., Blankley, Simon, McShane, Helen, O'Garra, Anne

Journal:

Microbial Pathogenesis

Year:

2013

Language:

english

File:

PDF, 830 KB

english, 2013

24

Comparing the safety and immunogenicity of a candidate TB vaccine MVA85A administered by intramuscular and intradermal delivery

Meyer, Joel, Harris, Stephanie A., Satti, Iman, Poulton, Ian D., Poyntz, Hazel C., Tanner, Rachel, Rowland, Rosalind, Griffiths, Kristin L., Fletcher, Helen A., McShane, Helen

Journal:

Year:

2013

Language:

english

File:

PDF, 804 KB

english, 2013

25

ALOIS: Alzheimer's and cognitive improvement studies register, a free, on-line register of dementia and cognitive enhancement trials (http://www.medicine.ox.ac.uk/alois/)

Reem Malouf, Anna Noel-Storr, Helen Collins, Rupert McShane, Lon S. Schneider

Journal:

Alzheimer's & Dementia

Year:

2009

Language:

english

File:

PDF, 64 KB

english, 2009

26

Lessons learnt from the first efficacy trial of a new infant tuberculosis vaccine since BCG

Tameris, Michele, McShane, Helen, McClain, J. Bruce, Landry, Bernard, Lockhart, Stephen, Luabeya, Angelique K.K., Geldenhuys, Hennie, Shea, Jacqui, Hussey, Gregory, van der Merwe, Linda, de Kock, Marw

Journal:

Year:

2013

Language:

english

File:

PDF, 228 KB

english, 2013

27

Tuberculosis vaccines in clinical trials

Rowland, Rosalind, McShane, Helen

Journal:

Expert Review of Vaccines

Year:

2011

Language:

english

File:

PDF, 550 KB

english, 2011

28

The next 10 years for tuberculosis vaccines: do we have the right plans in place?

Meyer, Joel, McShane, Helen

Journal:

Expert Review of Vaccines

Year:

2013

Language:

english

File:

PDF, 1011 KB

english, 2013

29

Rapid Detection of Mycobacterium tuberculosis Infection by Enumeration of Antigen-specific T Cells

LALVANI, AJIT, PATHAN, ANSAR A., McSHANE, HELEN, WILKINSON, ROBERT J., LATIF, MOHAMMED, CONLON, CHRISTOPHER P., PASVOL, GEOFFREY, HILL, ADRIAN V. S.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2001

Language:

english

File:

PDF, 151 KB

english, 2001

30

Tuberculosis vaccine trials – Authors' reply

Tameris, Michele, Hatherill, Mark, Mahomed, Hassan, McShane, Helen

Journal:

Year:

2013

Language:

english

File:

PDF, 132 KB

english, 2013

31

A review of preclinical animal models utilised for TB vaccine evaluation in the context of recent human efficacy data

McShane, Helen, Williams, Ann

Journal:

Year:

2014

Language:

english

File:

PDF, 251 KB

english, 2014

32

A review of the tolerability of the candidate TB vaccine, MVA85A compared with BCG and Yellow Fever vaccines, and correlation between MVA85A vaccine reactogenicity and cellular immunogenicity

Rowland, Rosalind, Brittain, Nathaniel, Poulton, Ian D, Minassian, Angela M, Sander, Clare, Porter, David W, Williams, Nicola, Satti, Iman, Pathan, Ansar A, Lawrie, Alison M, McShane, Helen

Journal:

Trials in Vaccinology

Year:

2012

Language:

english

File:

PDF, 586 KB

english, 2012

33

Editorial Board

Marsay, Leanne, Matsumiya, Magali, Tanner, Rachel, Poyntz, Hazel, Griffiths, Kristin L., Stylianou, Elena, Marsh, Philip D., Williams, Ann, Sharpe, Sally, Fletcher, Helen, McShane, Helen

Journal:

La Revue Sage-Femme

Year:

2011

Language:

french

File:

PDF, 58 KB

french, 2011

34

Mycobacterial growth inhibition in murine splenocytes as a surrogate for protection against Mycobacterium tuberculosis (M. tb)

Marsay, Leanne, Matsumiya, Magali, Tanner, Rachel, Poyntz, Hazel, Griffiths, Kristin L., Stylianou, Elena, Marsh, Philip D., Williams, Ann, Sharpe, Sally, Fletcher, Helen, McShane, Helen

Journal:

Year:

2013

Language:

english

File:

PDF, 921 KB

english, 2013

35

It's all in whom you know (as well as what you know). Using network analysis and health professionals own knowledge for recruitment

Charlene McShane,Olinda Santin,Helen McAneney,Michael Donnelly,Jackie Quinn…

Journal:

Year:

2013

Language:

english

File:

PDF, 121 KB

english, 2013

36

Biospecimen Reporting for Improved Study Quality (BRISQ)

Moore, Helen M., Kelly, Andrea B., Jewell, Scott D., McShane, Lisa M., Clark, Douglas P., Greenspan, Renata, Hayes, Daniel F., Hainaut, Pierre, Kim, Paula, Mansfield, Elizabeth, Potapova, Olga, Riegma

Journal:

Journal of Proteome Research

Year:

2011

Language:

english

File:

PDF, 5.05 MB

english, 2011

37

Development of a BCG challenge model for the testing of vaccine candidates against tuberculosis in cattle

Villarreal-Ramos, Bernardo, Berg, Stefan, Chamberlain, Laura, McShane, Helen, Hewinson, R. Glyn, Clifford, Derek, Vordermeier, Martin

Journal:

Year:

2014

Language:

english

File:

PDF, 434 KB

english, 2014

38

Heterologous vaccination against human tuberculosis modulates antigen-specific CD4 + T-cell function

Dintwe, One B., Day, Cheryl L., Smit, Erica, Nemes, Elisa, Gray, Clive, Tameris, Michele, McShane, Helen, Mahomed, Hassan, Hanekom, Willem A., Scriba, Thomas J.

Journal:

European Journal of Immunology

Year:

2013

Language:

english

File:

PDF, 934 KB

english, 2013

39

Biospecimen Reporting for Improved Study Quality

Moore, Helen M., Kelly, Andrea, Jewell, Scott D., McShane, Lisa M., Clark, Douglas P., Greenspan, Renata, Hainaut, Pierre, Hayes, Daniel F., Kim, Paula, Mansfield, Elizabeth, Potapova, Olga, Riegman,

Journal:

Biopreservation and Biobanking

Year:

2011

Language:

english

File:

PDF, 290 KB

english, 2011

40

Tuberculosis vaccines: present and future

Minassian, Angela M, McShane, Helen

Journal:

Expert Review of Respiratory Medicine

Year:

2008

Language:

english

File:

PDF, 398 KB

english, 2008

41

Biospecimen Reporting for Improved Study Quality (BRISQ)

Moore, Helen M., Kelly, Andrea, McShane, Lisa M., Vaught, Jim

Journal:

Transfusion (Wiley)

Year:

2013

Language:

english

File:

PDF, 37 KB

english, 2013

42

Developing an improved vaccine against tuberculosis

Journal:

Expert Review of Vaccines

Year:

2004

Language:

english

File:

PDF, 99 KB

english, 2004

43

Tuberculosis vaccine promises sterilizing immunity

McShane, Helen, Williams, Ann

Journal:

Nature Medicine

Year:

2011

Language:

english

File:

PDF, 254 KB

english, 2011

44

The human immune response to tuberculosis and its treatment: a view from the blood

Cliff, Jacqueline M., Kaufmann, Stefan H. E., McShane, Helen, van Helden, Paul, O'Garra, Anne

Journal:

Immunological Reviews

Year:

2015

Language:

english

File:

PDF, 1.59 MB

english, 2015

45

Tuberculosis vaccines: current status and future prospects

Fletcher, Helen, McShane, Helen

Journal:

Expert Opinion on Emerging Drugs

Year:

2006

Language:

english

File:

PDF, 325 KB

english, 2006

46

Individual-level factors associated with variation in mycobacterial-specific immune response: Gender and previous BCG vaccination status

Rhodes, Sophie J., Knight, Gwenan M., Fielding, Katherine, Scriba, Thomas J., Pathan, Ansar A., McShane, Helen, Fletcher, Helen, White, Richard G.

Journal:

Year:

2015

Language:

english

File:

PDF, 653 KB

english, 2015

47

A review of clinical models for the evaluation of human TB vaccines

O'Shea, Matthew K., McShane, Helen

Journal:

Human Vaccines & Immunotherapeutics

Year:

2016

Language:

english

File:

PDF, 1.18 MB

english, 2016

48

Optimization of a Human Bacille Calmette-Guérin Challenge Model: A Tool to Evaluate Antimycobacterial Immunity

Minhinnick, Alice, Harris, Stephanie, Wilkie, Morven, Peter, Jonathan, Stockdale, Lisa, Manjaly-Thomas, Zita-Rose, Vermaak, Samantha, Satti, Iman, Moss, Paul, McShane, Helen

Journal:

The Journal of Infectious Diseases

Year:

2016

File:

PDF, 425 KB

2016

49

Optimization of a Human Bacille Calmette-Guérin Challenge Model: A Tool to Evaluate Antimycobacterial Immunity

Minhinnick, Alice, Harris, Stephanie, Wilkie, Morven, Peter, Jonathan, Stockdale, Lisa, Manjaly-Thomas, Zita-Rose, Vermaak, Samantha, Satti, Iman, Moss, Paul, McShane, Helen

Journal:

The Journal of Infectious Diseases

Year:

2016

Language:

english

File:

PDF, 425 KB

english, 2016

50

From AIDS to TB vaccines — A career in infectious diseases and translational vaccinology

Journal:

Human Vaccines & Immunotherapeutics

Year:

2016

Language:

english

File:

PDF, 803 KB

english, 2016